Identifying potential introduced and natural sources of pollution in Delaware watersheds.

Managing water quality with microbial impairment caused by poses unique challenges regarding the determination of fecal host origin. Most water monitoring is performed based on counts that neither detect the location of the introduction of pollution nor identify the type of contaminating . The use of sequenced-based microbial source tracking could allow for identification of fecal origin and potential remediation of pollution.

Liver toxicity and repair evaluated by histopathology and electric modulus.

Detoxification is one of the most important liver functions. Therefore, liver is the front line of defense when the biosystem faces drug overdose, toxins, and anything that may cause harm. Some famous antibiotics are known for their side effects on liver; one of them is amoxicillin, AM.

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Biliary tract cancers (BTCs) are a group of deadly malignancies encompassing intrahepatic and extrahepatic cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. Here, we present the integrative analysis of 63 BTC cell lines via multi-omics clustering and genome- scale CRISPR screens, providing a platform to illuminate BTC biology and inform therapeutic development. We identify dependencies broadly enriched in BTC compared to other cancers as well as dependencies selective to the anatomic subtypes.