Publications by authors named "I Rouch"
Introduction: Adverse childhood events (ACEs) have been linked to widespread chronic pain (CP) in various cross-sectional studies, mainly in clinical populations. However, the independent role of different ACEs on the development of different types of CP remains elusive. Accordingly, we aimed to prospectively assess the associations between specific types of ACEs with the development of multisite CP in a large population-based cohort.
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- - This study explores how the premorbid personality of patients with mild Alzheimer's disease affects the burden on their caregivers, focusing on the influence of neuropsychiatric symptoms (NPS).
- - Researchers assessed 180 individuals with early Alzheimer's using personality tests, NPS evaluations, and caregiver burden scales, finding that higher NPS scores and certain personality traits (like high neuroticism and low conscientiousness) were linked to increased caregiver burden.
- - The findings indicate that caregivers may experience less burden when patients possess higher levels of extraversion and conscientiousness, suggesting that a patient's personality can significantly impact caregiver stress during early stages of Alzheimer's.
Article Synopsis
- Early psychological factors like childhood trauma and personality traits significantly contribute to nociplastic pain, which is pain not linked to specific tissue damage.
- Validating patients' pain experiences and understanding their unique histories are essential for effective care.
- A comprehensive treatment plan should adopt a bio-psycho-social model, focusing on psychotherapy alongside other therapeutic strategies.
Background: Apathy and depression are two early behavioral symptoms in Alzheimer's disease (AD) and related disorders that often occur prior to the onset of cognitive decline and memory disturbances. Both have been associated with an increased risk of conversion to dementia, with a distinct neuropathology.
Objective: The assessment of the trajectories of apathy and depression and their independent impact on dementia conversion.
Introduction: Lower cognitive functioning in old age has been associated with personality traits or systemic inflammatory markers. Associations have also been found between personality traits and inflammatory markers. However, no study has explored the inter-relationships between these three components simultaneously.
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