Publications by authors named "I Rospond-Kubiak"
Purpose: To explore the genetic background of choroidal and ciliary body melanoma among children and young adults, with special focus on BAP1 germline variants in this age group.
Methods: Patients under the age of 25 and with confirmed choroidal or ciliary body melanoma were included in this retrospective, multicenter observational study. Nuclear BAP1 immunopositivity was used to evaluate the presence of functional BAP1 in the tumor.
Aim: To investigate the frequency and location of additional primary malignancies in a Polish cohort of uveal melanoma (UM) patients registered in a single centre database.
Material And Method: Retrospective data analysis of patients treated for uveal melanoma at the Department of Ophthalmology, Poznań University of Medical Sciences, Poland between 1991 and 2017. Data on the diagnosis of the additional malignancies were obtained during the follow-up visits in our Department and/or from the Greater Poland Cancer Registry.
Radiation retinopathy following episcleral brachytherapy for intraocular tumors: Current treatment options.
J Contemp Brachytherapy
October 2023
Radiation retinopathy (RR) and radiation maculopathy (RM) can occur as a result of uveal melanoma radiation treatment and after irradiation of other head and neck extraocular tumors, even with precise targeting techniques, such as stereotactic or proton beam radiotherapy. This review provides an overview of the current understanding of potential radiation damage to ocular tissues, and how recent developments in ophthalmic multimodal imaging techniques and treatment modalities have improved managing options. Several treatment strategies have been employed so far for the management of RR, including laser photocoagulation, intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents or glucocorticosteroids and surgery.
View Article and Find Full Text PDFPurpose: The study aimed to review the long-term outcomes of ruthenium brachytherapy for iris and iridociliary melanoma.
Material And Methods: Medical records of patients who underwent ruthenium plaque treatment for iris and iridociliary melanoma at the Department of Ophthalmology, Poznań University of Medical Sciences, between 1999 and 2021 were retrospectively reviewed.
Results: We identified 24 patients, including 17 women and 7 men, with a median age of 61.
Article Synopsis
- The study aimed to evaluate the outcomes of acrylic orbital implant placements without using wrapping material in patients who underwent enucleation at Poznań University from 2013 to 2020.
- Out of 192 patients, predominantly female, the main reason for enucleation was uveal melanoma, and follow-up showed satisfactory implant stability with minimal complications, including 2% exposure rates.
- Most postoperative issues, such as eyelid malposition and thinning of Tenon's capsule, were linked to prior ocular surgeries, suggesting a generally positive outcome for unwrapped implants.