Publications by authors named "I Ron"
The combination of high energy fractures, extensive soft tissue trauma, and high infection rates in pilon fractures of the distal tibia have long challenged surgeons. Despite the ample evidence, there is no consensus regarding the factors that may influence postoperative infections following surgical management of these fractures. This study aimed to investigate the risk factors for postoperative infections in patients undergoing surgical management for pilon fractures.
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- Organophosphates (OP) are harmful chemicals used in agriculture and warfare, creating a need for effective detection methods that work quickly and are cost-effective, especially for detecting contamination in liquid samples.
- Current detection methods are only useful in the short term and fail to address long-term contamination risks, highlighting the need for real-time monitoring of OPs in water and soil.
- This study introduces a transistor-based sensor called MNChem, capable of ultra-sensitive, quantitative detection of diethyl cyanophosphonate (DCNP) in small liquid samples, achieving a detection limit of 100 fg/mL and a wide dynamic range, suggesting it’s suitable for on-site environmental analysis.*
Article Synopsis
- Transistor-based biosensing (BioFET) is explored as a promising method for future medical diagnostics but faces challenges with solution gating, as standard measurements affect the equilibrium of double layers where biomolecules interact.
- The study investigates a new BioFET design that separates the solution potential from the current gating process, allowing electrochemical equilibrium to be maintained while measuring biomolecule interactions.
- Results show that this decoupled approach significantly improves sensing performance for detecting ferritin in diluted plasma, achieving high sensitivity and a wide dynamic range compared to traditional methods.
Objective: Excessive consumption of added sugars has been linked to the rise in obesity and associated metabolic abnormalities. Non-nutritive sweeteners (NNSs) offer a potential solution to reduce sugar intake, yet their metabolic safety remains debated. This study aimed to systematically assess the long-term metabolic effects of commonly used NNSs under both normal and obesogenic conditions.
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- - The study focuses on using field-effect meta-nano-channel biosensors (MNC biosensors) to detect N-acetyl-beta-D-glucosaminidase (NAGase), an enzyme linked to infections in milk cows, in very small samples like 0.5 μL drops of milk.
- - The biosensor achieves highly specific and label-free sensing of NAGase with an impressive detection limit of 30.3 aM, spanning a dynamic range of eleven orders of magnitude, indicating strong linearity and sensitivity.
- - Two main findings highlight that despite the expected limitations due to the ionic strength and non-specific protein interactions in milk, the sensor works effectively, suggesting more research is needed on how non-specific