Publications by authors named "I Rivera Benitez"
Study Objectives: Actigraphy devices are used in sleep medicine. The Actiwatch 2 (Philips Respironics) was an example of a frequently used device in this field. Nevertheless, the discontinuation of this device has led to an increased necessity for the implementation of other available actigraphy methods capable of providing objective information.
View Article and Find Full Text PDFIntroduction: Understanding the diverse pathogenetic pathways in obstructive sleep apnea (OSA) is crucial for improving outcomes. microRNA (miRNA) profiling is a promising strategy for elucidating these mechanisms.
Objective: To characterize the pathogenetic pathways linked to OSA through the integration of miRNA profiles, machine learning (ML) and bioinformatics.
Objective: To describe the impact of the new intervention model implemented by Paraguay across five districts of the Central Region in the last quarter of 2023, consisting of an integrated health services-based strategy to recover coverage with the tracer vaccine (pentavalent until April 2023, hexavalent thereafter) in children under 1 year of age; and the measles, mumps, and rubella (MMR) vaccine for the 1-year-old population.
Methods: Descriptive, cross-sectional study with comparative analysis before (epidemiological weeks [EW] 1 and 34 of 2023) and after (EW35 and EW52 of 2023) the intervention. Three indicators were assessed: a) coverage with all three doses of pentavalent or hexavalent vaccine and first and second doses of MMR; b) productivity, represented by third doses of pentavalent or hexavalent vaccine administered; and c) dropout rates for the pentavalent or hexavalent and MMR vaccines.
Article Synopsis
- Obstructive sleep apnea (OSA) significantly impacts cardiovascular event recurrence in patients with acute coronary syndrome (ACS), particularly in those without prior cardiovascular disease.
- The study identified two groups based on the severity of OSA and utilized proteomics to analyze plasma proteins, revealing 24 differentially expressed proteins associated with OSA severity.
- Bioinformatic analysis suggested that these proteins are involved in key molecular pathways related to immune function, cell signaling, and inflammation, linking OSA to adverse cardiovascular outcomes.