Photochemical Hydroxyl Group Abstraction from -Hydroxypyridine-2(1)-thione Isolated in a Solid Hydrogen Matrix: Photogeneration of 2-Mercaptopyridine.

Monomers of -hydroxypyridine-2(1)-thione were isolated in low-temperature matrices of solid normal hydrogen (n-H). The matrix-isolated compound was irradiated with UV-B (λ = 305 nm) or UV-A (λ > 360 nm) light. Upon such irradiation, the initial form of -hydroxypyridine-2(1)-thione was completely consumed and converted into photoproducts.

Efficient delivery of carotenoids to adipocytes with albumin.

Carotenoids are very effectively delivered by albumin to adipocytes. The uptake of carotenoids to the cells occurs in the form of self-aggregates that localize in the vicinity of the adipocyte membrane, as shown by high spatial resolution Raman spectroscopy. The binding of carotenoids to albumin and the mechanism of their transport were elucidated with the help of chiroptical spectroscopies, in tandem with molecular docking and molecular dynamics simulations.

Methoxyacetone revisited.

Conformational space of methoxyacetone (MA) was studied at the MP2/6-311++G(d,p) and DFT(B3LYP)/6-311++G(d,p) levels of theory. Computations predict MA to adopt four conformations, resulting from internal rotations around the O=C-C-O (Trans, Cis) and C-C-O-C (trans, gauche) dihedral angles. The Tt (Trans-trans) conformer is the most stable.

Dual Photochemistry of Benzimidazole.

Monomers of benzimidazole trapped in an argon matrix at 15 K were characterized by vibrational spectroscopy and identified as 1-tautomers exclusively. The photochemistry of matrix-isolated 1-benzimidazole was induced by excitations with a frequency-tunable narrowband UV light and followed spectroscopically. Hitherto unobserved photoproducts were identified as 4- and 6-tautomers.