Algerian Workers' Exposure to Mycotoxins-A Biomonitoring Study.

Mycotoxins, produced by fungi as secondary metabolites, have the potential to induce both short-term and long-term toxic consequences in animals and humans. The present study aimed to determine multi-mycotoxin levels in Algerian workers using urine as the target. A method based on a QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was optimized and validated for the determination of eleven mycotoxins in 96 urine samples.

Urinary bisphenol levels in plastic industry workers.

Bisphenol A (BPA) is a known endocrine disruptor compound that is widely applied as a monomer base in polycarbonate plastics and as a binding agent in several epoxy resins. Plastic industry workers have usually heavier and prolonged exposures to BPA. Hence, the present work aims to assess the levels of BPA and their analogs (S, F, B, AF, Z, E, and AP) in 170 urine samples from a cross-sectional study of workers from a plastic industry located in north Constantine (Algeria).

Hypomyelination and Congenital Cataract: Clinical, Imaging, and Genetic Findings in Three Tunisian Families and Literature Review.

Hypomyelination and congenital cataract (HCC) is characterized by congenital cataract, progressive neurologic impairment, and diffuse myelin deficiency. This autosomal recessive disorder is caused by homozygous variant in the gene. Five consanguineous Tunisian patients, belonging to three unrelated families, underwent routine blood tests, electroneuromyography, and magnetic resonance imaging of the brain.

Severe dysautonomia as a main feature of anti-GAD encephalitis: Report of a paediatric case and literature review.

Introduction: Anti-glutamic acid decarboxylase (anti-GAD65) antibodies are a rare cause of autoimmune encephalitis. This entity is mainly recognized in adults and very few cases were reported in children. We report on a paediatric case of anti-GAD encephalitis with severe presentation and uncontrollable dysautonomia.

Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years.

Introduction: Pediatric multiple sclerosis (pMS) is a rare demyelinating disorder with an onset before the age of 18 years. In this study, we aimed to investigate the characteristics of pMS in Tunisian children.

Patients And Methods: We conducted a retrospective study over 11 years (2005-2016) including all patients diagnosed with pMS according to the International Pediatric Multiple Sclerosis Study Group (IPMSSG) criteria of 2012 and followed up in a tertiary care research center.