Publications by authors named "I Ratosa"

Article Synopsis
  • * The meeting involves discussion of pre-selected topics by working groups, which are informed by systematic reviews and surveys reflecting current clinical practices.
  • * The Assisi Working Group specifically examines lobular carcinoma, offering recommendations for locoregional therapy, especially radiation therapy for non-metastatic cases.
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Aim: To evaluate acute toxicity at 6 months after stereotactic body radiotherapy (SBRT) in patients with oligometastatic cancer within the OligoCare cohort.

Material And Methods: OligoCare is a prospective, registry-based, single-arm, observational study that aims to report prospective real-world data of patients with oligometastases from solid cancer treated with SBRT (NCT03818503). Primary tumor included non-small cell lung cancer (NSCLC), breast cancer (BC), colorectal cancer (CRC), and prostate cancer (PC).

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Purpose: Moderate hypofractionated radiotherapy is the standard of care for all patients with breast cancer, irrespective of stage or prior treatments. While extreme hypofractionation is accepted for early-stage tumours, its application in irradiating locoregional lymph nodes remains controversial.

Materials And Methods: A prospective registry analysis from July 2020 to September 2023 included 276 patients with early-stage breast cancer treated with one-week ultra-hypofractionation (UHF) at 26 Gy in 5 fractions on the whole breast (58.

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Article Synopsis
  • The study examines the optimal doses and fractionation in stereotactic body radiotherapy (SBRT) for patients with oligometastatic cancer, analyzing 1,099 registered patients from the OligoCare trial.
  • The analysis converted SBRT doses to biological effective doses (BED) using specific cancer types' α/β values, revealing that different cancers received varying doses based on type and metastasis locations.
  • Findings indicate that SBRT doses were adapted according to the primary cancers and metastasis sites, suggesting further research is needed on the safety and efficacy of this tailored approach.
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