Constitutive heterochromatin in higher eukaryotes is located in the primary chromosomal strangulation (centromeres and pericentromeres) and subtelomeric regions of chromosomes. In house mouse constitutive chromatin formes structures in the nuclei of cells, brightly colored with DAPI. It is known that the constitutive heterochromatin is enriched with large tandem repeats, however, its exact composition is unknown.
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