Publications by authors named "I R Porter"
Purpose: This study aimed to assess whether kidney stone burden and risk factors at the time of kidney donor evaluation were associated with a symptomatic stone event post-donor evaluation.
Methods: We identified adults evaluated at Mayo Clinic (two sites) (2000-2011) for living kidney donation and had either a personal history or radiological evidence of kidney stone disease. We analyzed demographics, stone risk factors, stone number/size, and the committee's donation decision and reasons.
Identifying noncoding single nucleotide variants ( SNVs ) in regulatory DNA linked to polygenic disease risk, the transcription factors ( TFs ) they bind, and the target genes they dysregulate is a goal in polygenic disease research. Massively parallel reporter gene analysis ( MPRA ) of 3,451 SNVs linked to risk for polygenic skin diseases characterized by disrupted epidermal homeostasis identified 355 differentially active SNVs ( daSNVs ). daSNV target gene analysis, combined with daSNV editing, underscored dysregulated epidermal differentiation as a pathomechanism shared across common polygenic skin diseases.
View Article and Find Full Text PDFObjective: To provide a video tutorial on the diagnostic ultrasound approach to the medial compartment of the canine shoulder and provide comparisons of normal and pathological images with corresponding MRI.
Animals: Dogs undergoing diagnostic ultrasound of the medial shoulder.
Methods: The medial shoulder was positioned in flexion with external rotation to allow transducer access, clipped, and scrubbed with dilute chlorhexidine.
Article Synopsis
- - The International Survey of People living with Chronic Conditions (OECD-PaRIS) focuses on gathering patient-reported experiences and outcomes for individuals with chronic illnesses, while also examining the quality of healthcare provided by general practitioners (GPs).
- - A field trial was conducted in Norway where 75 GPs and several patients (125 per GP) were randomly sampled to assess differences in patient experiences based on GP participation in the survey.
- - Results showed that only 22.7% of GPs participated, leading to about half of patients responding; significant differences were noted in the experiences reported by patients from participating GPs compared to non-participating GPs.
Unlabelled: BackgroundThe Organisation for Economic Co-operation and Development (OECD) Patient-Reported Indicator Surveys (PaRIS) initiative aims to support countries in improving care for people living with chronic conditions by collecting information on how people experience the quality and performance of primary and (generalist) ambulatory care services. This paper presents the development of the conceptual framework that underpins the rationale for and the instrumentation of the PaRIS survey.
Methods: The guidance of an international expert taskforce and the OECD Health Care Quality Indicators framework (2015) provided initial specifications for the framework.