Non-invasive in vivo sensing of bacterial implant infection using catalytically-optimised gold nanocluster-loaded liposomes for urinary readout.

Staphylococcus aureus is a leading cause of nosocomial implant-associated infections, causing significant morbidity and mortality, underscoring the need for rapid, non-invasive, and cost-effective diagnostics. Here, we optimise the synthesis of renal-clearable gold nanoclusters (AuNCs) for enhanced catalytic activity with the aim of developing a sensitive colourimetric diagnostic for bacterial infection. All-atom molecular dynamics (MD) simulations confirm the stability of glutathione-coated AuNCs and surface access for peroxidase-like activity in complex physiological environments.

Infrared thermochromic antenna composite for self-adaptive thermoregulation.

Self-adaptive thermoregulation, the mechanism living organisms use to balance their temperature, holds great promise for decarbonizing cooling and heating processes. This functionality can be effectively emulated by engineering the thermal emissivity of materials to adapt to background temperature variations. Yet, solutions that marry large emissivity switching ( ) with scalability, cost-effectiveness, and design freedom are still lacking.

Quantitative multiplexing of uric acid and creatinine using polydisperse plasmonic nanoparticles enabled by electrochemical-SERS and machine learning.

Surface-enhanced Raman spectroscopy (SERS) is a promising technique for the detection of biomarkers, but it can struggle to quantify multiple analytes in complex fluids. This study combines electrochemical SERS (E-SERS) and machine learning for the quantitative multiplexed detection of uric acid (UA) and creatinine (CRN). Using classical polydisperse Ag nanoparticles (NPs) made by scalable synthesis, we achieved quantitative multiplexing with low limits of detection (LoDs) and high prediction accuracy, comparable to those made by sophisticated approaches.

Ferroelectric Interfaces for Dendrite Prevention in Zinc-Ion Batteries.

Aqueous rechargeable zinc-ion batteries (ZIBs) are increasingly recognized as promising energy storage systems for mini-grid and mini-off-grid applications due to their advantageous characteristics such as high safety, affordability, and considerable theoretical capacity. However, the long-term cycling performance of ZIBs is hampered by challenges including the uncontrolled dendrite formation, the passivation, and the occurrence of the hydrogen evolution reaction (HER) on the Zn anode. In this study, enhancing ZIB performance by implementing oxide material coatings on Zn metal, serving as a physical barrier at the electrode-electrolyte interfaces to mitigate dendrite growth and suppress the HER is concentrated.