Publications by authors named "I R Mertens zur Borg"

Article Synopsis
  • Hidradenitis suppurativa (HS) is a genetic skin condition that can have a hereditary basis in some cases, particularly linked to changes in the NCSTN gene.
  • A study aimed to find the prevalence of a specific NCSTN gene variant and its effects on HS symptoms among patients in Malta.
  • Out of 113 HS patients studied, 14 (about 12.4%) carried the NCSTN variant, with the majority experiencing their first symptoms around age 18.
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Genetic research has identified a large number of genetic variants, both rare and common, underlying neurodevelopmental disorders (NDD) and major psychiatric disorders. Currently, these findings are being translated into clinical practice. However, there is a lack of knowledge and guidelines for psychiatric genetic testing (PsychGT) and genetic counseling (PsychGC).

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Individuals tend to be most mobile when they are between 20 and 40 years of age. This pattern is relatively stable across regions and over time. For geographical mobility, less is known about their transitions between different types of housing and tenure forms.

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Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the pilosebaceous unit characterized by inflammation and hyperkeratinization. A small but significant proportion of patients with HS have a strong genetic susceptibility to (or a syndromic form of) the disease. Current HS treatment guidelines prioritize patients who manifest classic HS and may therefore not be suitable for the minority of patients harbouring genetically driven forms of disease.

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