Publications by authors named "I R Mann"

Article Synopsis
  • Human herpesviruses (HHVs) can cause serious brain infections like meningitis and encephalitis.
  • HHV-8, usually not linked to brain issues, was found to cause encephalitis in a patient who had just received an organ transplant and had a related disease called Kaposi's Sarcoma.
  • The patient was treated with special antiviral medicine, showing that it's important for doctors to be aware of HHV-8 risks in transplant patients.
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Background: Epicardial ablation complications are more frequent in patients with preexisting pericardial adhesions. As opposed to the dry puncture technique, the coronary vein exit and carbon dioxide (CO) insufflation (EpiCO) technique allows diagnosing pericardial adhesions before subxiphoid puncture.

Objective: This study aimed to evaluate the efficacy of the EpiCO technique in diagnosing pericardial adhesions prior to subxiphoid puncture.

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RETRO-mapping was developed to automate activation mapping of atrial fibrillation (AF). We used the algorithm to study the effect of pulmonary vein isolation (PVI) on the frequency of focal, planar, and colliding wavefronts in persistent AF. An AFocusII catheter was placed on the left atrial endocardium to record 3 s of AF at six sites pre and post-PVI in patients undergoing wide circumferential PVI for persistent AF.

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Electrical conduction through cardiac muscle fibres separated from the main myocardial wall by layers of interposed adipose tissue are notoriously difficult to target by endocardial ablation alone. They are a recognised important cause for procedural failure due to the difficulties of delivering sufficient energy via the endocardial radiofrequency catheter to reach the outer epicardial layer without risking adverse events of the otherwise thin walled atria. Left atrial ablations for atrial fibrillation (AF) and tachycardia are commonly affected by the presence of several epicardial structures, with the septo-pulmonary bundle (SPB), Bachmann's bundle, and the ligament of Marshall all posing substantial challenges for endocardial procedures.

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