Publications by authors named "I R Holzman"
Purpose: We conducted a consented pilot newborn screening (NBS) for Pompe, Gaucher, Niemann-Pick A/B, Fabry, and MPS 1 to assess the suitability of these lysosomal storage disorders (LSDs) for public health mandated screening.
Methods: At five participating high-birth rate, ethnically diverse New York City hospitals, recruiters discussed the study with postpartum parents and documented verbal consent. Screening on consented samples was performed using multiplexed tandem mass spectrometry.
Article Synopsis
- - Sudden unexpected neonatal collapse is rare but can happen to healthy term infants, especially during breastfeeding due to improper positioning.
- - Two cases of respiratory arrest in healthy newborns occurred while being held by their mothers during breastfeeding, but quick actions by the delivery room nurse prevented serious outcomes.
- - It's essential to educate mothers on safe positioning of newborns to prevent respiratory issues during breastfeeding, as both babies recovered well after medical evaluations showed no significant problems.
We argue that the "best interest standard" for surrogate decision-making is problematic for a number of reasons. First, reliance on the best interest standard is subjective. Second, it leads to behavior that is intolerant and polarizing.
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