Publications by authors named "I R Gaĭsin"
Article Synopsis
- * After 30 minutes of plasma treatment, the amount of flavan-3-ols, important for preventing browning, decreased a lot due to possible breakdown from stress caused by the plasma.
- * Although these helpful compounds went down, the treatment also increased other good stuff like dihydrochalcones and flavonols, which might improve the apples' flavor and health benefits!
A series of previously unknown aromatic polyether macrodiolides containing a -1,5-diene moiety in the molecule were synthesized in 47-74% yields. Macrocycle compounds were first obtained by intermolecular esterification of aromatic polyether diols with α,ω-alka-nZ,(n+4)Z-dienedioic acids mediated by -(3-(dimethylamino)propyl)-'-ethylcarbodiimide hydrochloride (EDC·HCl) and 4-(dimethylamino)pyridine (DMAP). For the synthesized compounds, studies of cytotoxicity on tumor (Jurkat, K562, U937), conditionally normal (HEK293) cell lines, and normal fibroblasts were carried out.
View Article and Find Full Text PDFBackground The prevalence of ischemic heart disease (IHD) in women of child-bearing age is rising. Data on pregnancies however are scarce. The objective is to describe the pregnancy outcomes in these women.
View Article and Find Full Text PDFAt present, compelling evidence has been obtained that combined therapy of pulmonary arterial hypertension (PAH) with specific drugs can significantly slow progression of PAH. Therefore, in current guidelines combination therapy is already considered as standard treatment for a significant proportion of patients with moderately severe and severe forms of PAH. However, the quality of life and long-term prognosis of patients receiving combination therapy, should be the object of further research.
View Article and Find Full Text PDFAims: We report the maternal and foetal outcomes at birth and after 6 months in a cohort of pregnant women with hypertrophic cardiomyopathy (HCM). Although most women with HCM tolerate pregnancy well, there is an increased risk of obstetric and cardiovascular complications.
Methods And Results: All pregnant women with HCM entered into the prospective worldwide Registry of Pregnancy and Cardiac disease (ROPAC) were included in this analysis.