Publications by authors named "I R Avila"
Objectives: To describe the main dengue metrics generated by the Global Burden of Disease (GBD) Study 2019 for South American countries between 1990 and 2019.
Study Design: A descriptive study was carried out using the metrics obtained by the GBD Study 2019.
Methods: The metrics of incidence, years of life lost due to premature death (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) were evaluated, grouped by sex and country, between 1990 and 2019.
We previously showed that inhibition of glycolysis in cutaneous squamous cell carcinoma (SCC)-initiating cells had no effect on tumorigenesis, despite the perceived requirement of the Warburg effect, which was thought to drive carcinogenesis. Instead, these SCCs were metabolically flexible and sustained growth through glutaminolysis, another metabolic process frequently implicated to fuel tumorigenesis in various cancers. Here, we focused on glutaminolysis and genetically blocked this process through glutaminase (GLS) deletion in SCC cells of origin.
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- The study focuses on the gasification kinetics of Brazilian municipal solid waste (MSW) and highlights the ignition properties of paper and plastic compared to food waste, noting that paper and plastic ignite significantly faster.
- Paper waste has minimum energy values of 132 kJ/mol (air) and 140 kJ/mol (air/CO), while MSW shows an average energy value of 96 kJ/mol in CO conditions, indicating varying energy requirements for gasification.
- The combination of air and CO significantly enhances the oxidation and gasification processes of waste components, leading to improved combustion efficiency and reduced CO emissions in waste-to-energy applications.
Article Synopsis
- Burnout is defined as a syndrome involving emotional exhaustion, cynicism, and decreased effectiveness, often due to long-term job stress, and has been worsened by the COVID-19 pandemic, particularly among healthcare workers in Brazil.
- A study surveying 143 hospital workers found a high prevalence of burnout at 53.85%, with the 'frenetic' subtype being the most common, where individuals overexert themselves to meet demands at the cost of personal needs.
- The study highlights the importance of tailored interventions based on burnout subtypes and notes that younger workers (under 51) experience higher burnout levels, indicating a need for preventative measures in the healthcare sector.