Publications by authors named "I Quiles-Melero"
Article Synopsis
- Respiratory infections significantly affect hospitalization rates and costs for children with tracheostomies, prompting a study on antibiotic treatment patterns.
- The research analyzed medical records of 83 children to evaluate antibiotic use for tracheobronchitis and nonspecific respiratory episodes (NSRE), revealing that a high percentage of tracheobronchitis cases received antibiotics, while many NSRE cases did not require them.
- Factors like fever were linked to increased antibiotic prescriptions, but many cases resolved without treatment, indicating the need for careful antibiotic prescription practices to avoid unnecessary usage.
Clinical Utility of a Multiplex PCR Panel (BioFire Joint Infection) in the Adjustment of Empiric Antimicrobial Therapy: Experience in Pediatric Osteoarticular Infections.
Children (Basel)
October 2024
Background/objectives: This study aims to evaluate the impact of the PCR multiplex panel (BioFire JI) on the diagnosis and management of pediatric osteoarticular infections.
Methods: This retrospective study analyzed data from pediatric patients diagnosed with osteoarticular infections between January 2023 and April 2024. The effectiveness of the PCR multiplex panel in identifying pathogens was compared with traditional culture methods.
Utility of culture and molecular methods using Allplex Bacterial Vaginosis Plus Assay (Seegene) as a tool for endometriosis, infertility and recurrent pregnancy loss diagnosis.
Diagn Microbiol Infect Dis
November 2024
Endometriosis, infertility, or recurrent pregnancy loss (RPL) are entities characterised by a decrease in Lactobacillus spp. and an increase in bacterial vaginosis-associated bacteria, (BVAV) according with 16S rRNA sequencing studies. However, the use of nucleic acid amplification tests (NAAT) as a tool for diagnosis algorithms is unknown.
View Article and Find Full Text PDFGlobally, an increase in sexually transmitted diseases worldwide has been reported, including acquired infection. Congenital syphilis is the mother-to-child transmission syphilis infection, experiencing an increase in cases returning to incidence rates of years ago. We report three cases of symptomatic congenital syphilis occurring in a tertiary-care hospital in Madrid (Spain).
View Article and Find Full Text PDFArticle Synopsis
- This study aims to quickly and accurately detect the Y132F ERG11p mutation in Candida parapsilosis isolates and to analyze genetic diversity among these isolates for better tracking of fluconazole resistance.!* -
- The research involved 223 isolates from patients across 20 hospitals in Spain and Italy, using newly optimized PCR methods that require no DNA extraction and provide results in as little as 1.5 hours.!* -
- The findings confirm both PCR methods have 100% specificity and sensitivity, with Scheme 1 showing greater genetic diversity compared to Scheme 2, suggesting the use of specific microsatellite markers for better genotyping of resistant strains.!*