Publications by authors named "I Predescu"

Cutaneous melanoma (CM) represents a severe skin cancer with a rising incidence at present and limited treatment options. 5-Fluorouracil (5-FU) is widely used, including for CM; however, the innate resistance of this cancer to conventional therapy remains problematic. Quercetin (QUE) is a flavonoid that can sensitize cancer cells to antitumor agents such as 5-FU.

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Background: Plants have long been recognized for their potential to influence neurological health, with both neuroprotective and neurotoxic properties. This review explores the dual nature of plant-derived compounds and their impact on the human brain.

Discussion: Numerous studies have highlighted the neuroprotective effects of various phytoconstituents, such as those found in , , , , and .

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Article Synopsis
  • * In vitro tests on healthy skin cell lines showed that the hydrogels had a good biosafety profile, with no significant toxicity or harmful effects observed after exposure.
  • * Additional in vivo studies on mice and chicken embryos confirmed the hydrogels' biocompatibility, but further research is necessary to assess their long-term therapeutic effects and clinical application potential.
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