Insulin resistance in tetraplegia but not in mid-thoracic paraplegia: is the mid-thoracic spinal cord involved in glucose regulation?

Study Design: Controlled experimental human study.

Objectives: To assess insulin resistance (IR) in tetraplegia and paraplegia, and the role of the spinal cord (SC) in glucose regulation.

Setting: Laboratory of Spinal Research, Loewenstein Rehabilitation Hospital.

Hemodynamic responses to head-up tilt after spinal cord injury support a role for the mid-thoracic spinal cord in cardiovascular regulation.

Background: Data showing a role for the mid-thoracic spinal cord (SC) in the control of hemodynamic changes is scarce despite existing evidence for its involvement in autonomic regulation.

Study Design: On the basis of the open label prospective series comparing three groups.

Objective: To determine whether the mid-thoracic SC has a role in hemodynamic regulation during head-up tilt (HUT).

Modified cold pressor test by cold application to the foot after spinal cord injury: suggestion of hemodynamic control by the spinal cord.

Objective: Study hemodynamic responses to cold application to the foot (CAF) to explore the autonomic cardiovascular control by the spinal cord.

Design: Controlled experimental study. Hemodynamic variables were measured or calculated for 13 healthy subjects, 10 patients with traumatic T4-T6 paraplegia, and 11 patients with traumatic C4-C7 tetraplegia.

Cold pressor test in tetraplegia and paraplegia suggests an independent role of the thoracic spinal cord in the hemodynamic responses to cold.

Background: Cold application to the hand (CAH) is associated in healthy people with increase in heart rate (HR) and blood pressure (BP).

Objective: To study hemodynamic responses to CAH in humans following spinal cord injuries of various levels, and examine the effect of spinal cord integrity on the cold pressor response.

Design: An experimental controlled study.

Evaluation of autonomic function underlying slow postexercise heart rate recovery.

Unlabelled: The reduction in heart rate (HR) during the first minute of recovery immediately after a graded maximal exercise stress test (GXT) has recently been found to be a powerful and independent predictor of cardiovascular and all-cause mortality. Reduced vagal activity has been postulated as the cause, but this has not been proven in a population with slow HR recovery (HRR).

Purpose: To investigate autonomic contributions to HRR using time-frequency analysis in a group of individuals demonstrating slow HRR.