Publications by authors named "I Pilic"
: Mutations in succinate dehydrogenase (SDH) and fumarate hydratase (FH) give rise to various familial cancer syndromes, with these alterations being characteristic of certain types of histomorphologically specific leiomyomas that hold significant predictive value. : This study presents two cases of uterine leiomyomas exhibiting rare histomorphological and genetic characteristics, which are crucial for prognosis and further treatment. : Distinct histopathological features such as marked nuclear atypia, intracellular eosinophilic globules, and abnormal intratumoral vessels raise suspicion for specific leiomyoma subtypes, which carry predictive significance for additional hereditary cancer syndromes.
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- Cancer during pregnancy poses significant risks for both mothers and their children, with this study examining outcomes for 84 women diagnosed with tumors from 2001 to 2022.
- Mothers mainly experienced gynecological or hematological cancers, most commonly diagnosed in the second trimester, and about two-thirds of the pregnancies ended in preterm deliveries to facilitate maternal treatment.
- The study found high survival rates for mothers (95.2% during pregnancy, 87.5% after one year) and their children (94% during pregnancy, with 76.2% surviving one year), though many mothers continued to require treatment post-delivery.
Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing fibro-cutaneous tumor of low to intermediate grade malignancy. It is characterized by local dermal and subcutaneous infiltration, but also with destructive infiltration of the surrounding tissues (muscle, fascia, and bone). The size of the tumor varies from small nodular to large neglected masses.
View Article and Find Full Text PDFFetal hydrops and middle cerebral artery Doppler in prediction degree of fetal anemia and the best timing for therapy.
Clin Exp Obstet Gynecol
August 2018
Purpose: To determine the role of fetal multiples of the median of middle cerebral artery peak systolic velocity (MoM MCA-PSV), in predicting the degree of fetal anemia for determination of the best timing for the second intrauterine intravascular transfusion (IUIVT) in hydropic fetuses with Rh alloimmunization.
Materials And Methods: Prospective study of 30 monofetal pregnancies with maternal Rh D alloimmunization and hydrops fetalis, from 2005 to 2012 that underwent first and second IUIVT were assessed.
Results: Thirty IUIVT were performed at 26.
Purpose: Advances in cardiac surgery significantly improve life expectancy and quality of life of patients with congenital or acquired heart disease.
Materials And Methods: The present study included 146 pregnant women who had antenatal care and gave birth at the Institute of Gynecology and Obstetrics in an interval of ten years from 1994-2004. Patients were divided in four groups according to the type of heart surgery.