Publications by authors named "I Petrache"
Lung Endothelial Cell Heterogeneity in Health and Pulmonary Vascular Disease.
Am J Physiol Lung Cell Mol Physiol
January 2025
Lung endothelial cells (ECs) are essential for maintaining organ function and homeostasis. Despite sharing some common features with ECs from organ systems, lung ECs exhibit significant heterogeneity in morphology, function, and gene expression. This heterogeneity is increasingly recognized as a key contributor to the development of pulmonary diseases like pulmonary hypertension (PH).
View Article and Find Full Text PDFThe Great Saphenous Vein Proximal Part: Branches, Anatomical Variations, and Their Implications for Clinical Practice and Venous Reflux Surgery.
J Cardiovasc Dev Dis
August 2024
Article Synopsis
- * It found that GSV diameter increases with the complexity of anatomical features, which can include multiple tributaries or other abnormalities, correlating significantly with chronic venous disease (CVD) stages.
- * The research underscores the need to recognize these variations for better surgical outcomes, supporting personalized treatment strategies for patients with venous reflux related to CVD.
Article Synopsis
- - A study analyzed 187 non-small-cell lung cancer patients to investigate how inflammation-related markers affect their prognosis and treatment outcomes.
- - Key findings included significantly higher neutrophil-to-lymphocyte ratio (NLR) and other inflammation ratios in advanced-stage patients and smokers, indicating a relationship between inflammation and cancer severity.
- - The research highlighted that higher levels of NLR correlated with larger tumor sizes and that certain inflammatory markers could help predict complications after surgery, emphasizing their role in patient management.
Article Synopsis
- This study examines the effects of the COVID-19 pandemic on lung cancer surgical treatments by comparing data from surgeries performed during the pandemic to those before and after.
- Key findings include a significant decrease in surgical procedures during the pandemic, an increase in cancer severity (T stage), and a rise in patient comorbidities during that time.
- The analysis also noted reduced hospitalization times during the pandemic, indicating major shifts in clinical practices and strategies for lung cancer care during this crisis.
Background: Despite advancements in coronary artery bypass grafting (CABG), the optimal choice of graft material remains a subject of investigation. This study aimed to comprehensively analyze the morphological characteristics of varicose veins, exploring their potential utilization in CABG compared to healthy veins.
Methods: The study included 178 patients, categorized into two groups based on healthy and varicose veins.