Publications by authors named "I Perez-Camacho"
Association of microbiological factors with mortality in Escherichia coli bacteraemia presenting with sepsis/septic shock: a prospective cohort study.
Clin Microbiol Infect
August 2024
Objectives: This study aimed to determine the association of Escherichia coli microbiological factors with 30-day mortality in patients with bloodstream infection (BSI) presenting with a dysregulated response to infection (i.e. sepsis or septic shock).
View Article and Find Full Text PDFWhole-genome characterisation of Escherichia coli isolates from patients with bacteraemia presenting with sepsis or septic shock in Spain: a multicentre cross-sectional study.
Lancet Microbe
April 2024
Article Synopsis
- - The study focuses on characterizing *Escherichia coli* (E. coli) blood isolates that cause sepsis or septic shock, as these infections are common and often severe, leading to critical health outcomes in affected patients.
- - Data from a multicenter study in Spain involved whole-genome sequencing of E. coli blood isolates from patients over 14 with diagnosed sepsis or septic shock, identifying various microbiological features, including phylogroups, sequence types, virulence factors, and antimicrobial resistance (AMR) genes.
- - Results showed that most isolates belonged to phylogenetic group 1, with specific sequence types such as ST131 and ST73 being the most common, but there were no significant geographical
Article Synopsis
- - The study investigates how HIV affects the severity of mpox outcomes in a large group of patients from 18 hospitals in Spain, focusing on factors like duration of illness and the presence of complications.
- - Out of 1,823 patients with PCR-confirmed mpox, around 43% were people living with HIV, with a significant portion having uncontrolled viral loads, leading to higher rates of long or complicated mpox.
- - The findings suggest that individuals with uncontrolled HIV are at increased risk for severe mpox complications, highlighting the need for timely HIV testing and immediate antiretroviral therapy for those diagnosed.
Background: The Clinical Trial of Sarilumab in Adults With COVID-19 (SARICOR) showed that patients with coronavirus disease 2019 (COVID-19) pneumonia and increased levels of interleukin (IL)-6 might benefit from blockade of the IL-6 pathway. However, the benefit from this intervention might not be uniform. In this subanalysis, we sought to determine if other immunoactivation markers, besides IL-6, could identify which subgroup of patients benefit most from this intervention.
View Article and Find Full Text PDFConventional Hospitalization versus Sequential Outpatient Parenteral Antibiotic Therapy for Bacteremia: Post-Hoc Analysis of a Multicenter Observational Cohort.
Antibiotics (Basel)
January 2023
It is not known whether sequential outpatient parenteral antimicrobial (OPAT) is as safe and effective as conventional hospitalization in patients with S. aureus bacteremia (SAB). A post-hoc analysis of the comparative effectiveness of conventional hospitalization versus sequential OPAT was performed in two prospective Spanish cohorts of patients with S.
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