Abnormal electrical brain responses to time deviance in beat deafness.

Humans have the spontaneous capacity to track the beat of music. Yet some individuals show marked difficulties. To investigate the neural correlates of this condition known as beat deafness, the cortical electric activity of ten beat-deaf adults, the largest cohort studied so far, as well as of 14 matched controls (Experiment 2), and 16 university students (Experiment 1) were examined.

Seeing the Trees From the Forest: Challenges in Subgroup Analysis-Based Guidelines in Oncology.

As clinical trials in oncology require substantial efforts, maximizing the insights gained from them by conducting subgroup analyses is often attempted. The goal of these analyses is to identify subgroups of patients who are likely to benefit, as well as the subgroups of patients who are unlikely to benefit from the studied intervention. International guidelines occasionally include or exclude novel medications and technologies for specific subpopulations based on such analyses of pivotal trials without requiring confirmatory trials.

Diamond-based microwave quantum amplifier.

Amplification of weak microwave signals with minimal added noise is of importance to science and technology. Artificial quantum systems, based on superconducting circuits, can now amplify and detect even single microwave photons. However, this requires operating at millikelvin temperatures.