Molecular-based laboratory testing confer accuracy over microscopical testing for tick identification.

As per published literature, the tick is the primary Lyme disease vector in British Columbia (BC), while the tick species is the dominant vector on the East Coast of Canada, with no . presence seen in BC. However, a recent publication reported presence of in BC which initiated this study to determine the accuracy of the microscopic identification of ticks received in the BC Centre for Disease Control (BCCDC) Public Health Laboratory and compare morphologic methods to molecular methods.

Reduced circulating sphingolipids and activity are linked to T2D risk and impaired insulin secretion.

Gestational diabetes mellitus (GDM), a transient form of diabetes that resolves postpartum, is a major risk factor for type 2 diabetes (T2D) in women. While the progression from GDM to T2D is not fully understood, it involves both genetic and environmental components. By integrating clinical, metabolomic, and genome-wide association study (GWAS) data, we identified associations between decreased sphingolipid biosynthesis and future T2D, in part through the allele of the gene in Hispanic women shortly after a GDM pregnancy.

Sustainable oxalic acid treatment of lignocellulosic fibers for ensuring improved performance of treated fibers based bio PBS composites.

Plant-based macromolecules such as lignocellulosic fibers are one of the promising bio-resources to be utilized as reinforcement for developing sustainable composites. However, due to their hydrophilic nature and weak interfacial bonding with polymer matrices, these fibers are mostly incompatible with biopolymers. The current research endeavor explores the novel eco-friendly oxalic acid (CHO.

Identification of CD8+ Immunogenic Peptides for Vaccine Design against Nipah Virus in Humans.

Background: Nipah virus is a pathogenic virus of ruinous zoonotic potential with inflated rate of mortality in humans.

Methods: Considering the emerging threat of this pandemic virus, the present investigation amid to design vaccine by using the bioinformatics tools such as host and virus codon usage analysis, CD8+ peptide prediction, immunogenicity/allergenicity/toxicity, MHC-I allele binding prediction and subsequent population coverage and MHC-I-peptide docking analysis.

Results: In this study (conducted in 2022 at School of Biotechnology, Katra, India), a set of 11 peptides of the structural proteins of Nipah Virus were predicted and recognized by the set of MHC-I alleles that are expressed in 92% of the global human population.

Recent progress in nanomaterial-based electrochemical biosensors for hydrogen peroxide detection & their biological applications.

The electrochemical biosensor has brought a paradigm shift in the field of sensing due to its fast response and easy operability. The performance of electrochemical sensors can be modified by coupling them with various metal oxides, nanomaterials, and nanocomposites. Hydrogen peroxide is a short-lived reactive oxygen species that plays a crucial role in various physiological and biological processes.