[Cholescintigraphy and hepatic clearance of 99mTc-p-butyl HIDA in Gilbert's syndrome].

99mTc-p-butyl IDA clearance was measured in three subjects with Gilbert's syndrome at the same time as traditional cholescintigraphy. Cholescintigraphy persistently revealed a delayed liver display together with a normal fast display of the biliary ways. The Tu (semi-uptake time) of 99mTc-p-butyl IDA was higher in all three cases than in normal subjects, whereas Te (semisecretion time) was normal in all cases.

[Hepatic clearance of 99mTc-p-butyl HIDA in liver diseases. Correlations with routine hematochemical parameters of liver function].

The aim of the present investigation was to study the clearance of 99mTc-p-butyl IDA in some acute and chronic liver diseases, it being considered that the typical parameters obtained with this method are as indicative as any of the others put forward for the study of liver function using radioisotopes. 46 subjects were examined: 6 with acute hepatitis, 10 with chronic hepatitis, 18 with liver cirrhosis and 12 with dyspepsia but otherwise normal haematochemical tests. Two basic 99mTc-p-butyl IDA clearance parameters, Tu (semi-take up time) and Te (semi-excretion time), were determined plotting the data obtained using a Gamma-Camera on semi-logarithmic paper.