Publications by authors named "I Papagiannis"
Background/objective: Li-Fraumeni syndrome (LFS) is an inherited sequence variant in TP53 characterized by the early onset of various core malignancies including adrenocortical carcinoma (ACC), sarcomas, breast cancer, leukemias, and central nervous system tumors. We present a case of a patient with LFS who developed endocrine neoplasms not classically seen in LFS in addition to developing ACC.
Case Report: A 26-year-old nonbinary individual assigned female at birth with a history of LFS complicated by osteosarcoma of the jaw was incidentally found to have thyroid and sellar masses on surveillance magnetic resonance imaging.
Article Synopsis
- The study focuses on pediatric cardiomyopathy in children under 18 in Crete, Greece, aiming to assess its epidemiology from 2002 to 2022.
- The annual incidence was found to be 1.59 cases per 100,000 children, with dilated cardiomyopathy being the most common type (50%).
- The research indicates a higher incidence of pediatric cardiomyopathy in Crete compared to other Caucasian populations, suggesting a need for further examination of genetic factors in this demographic.
Paediatric cardiomyopathies form a heterogeneous group of disorders characterized by structural and electrical abnormalities of the heart muscle, commonly due to a gene variant of the myocardial cell structure. Mostly inherited as a dominant or occasionally recessive trait, they might be part of a syndromic disorder of underlying metabolic or neuromuscular defects or combine early developing extracardiac abnormalities (i.e.
View Article and Find Full Text PDFBackground: Ferredoxin reductase (FDXR) has already been reported as a promising biomarker for estimating radiation doses in radiotherapy. This study aimed to investigate the responsiveness of FDXR on pediatric population exposed to ionizing radiation (X-rays) during pediatric interventional cardiology (IC) procedures.
Patients And Methods: Peripheral blood was collected by venipuncture from 24 pediatric donors before and 24 hours after the IC procedure.
Effect of the COVID-19 pandemic on cardiac electrophysiological ablation procedures in Greece - Data from the Hellenic Society of Cardiology Ablation Registry.
Hellenic J Cardiol
September 2022