Publications by authors named "I Palacin"
Article Synopsis
- Metabolic dysfunction-associated steatotic liver disease (MASLD) affects about 30% of the global population, driven by a mix of genetic, lifestyle, and environmental factors, complicating treatment and clinical trial design.* -
- The study utilized a liver acinus microphysiology system (LAMPS) made from patient-derived cells to explore the effects of the PNPLA3 rs738409 genetic variant on MASLD progression, replicating various metabolic conditions.* -
- Results showed that the PNPLA3 GG variant led to increased liver fat, immune activation, and pro-fibrotic factor secretion compared to wild type cells, providing insights for future treatments like resmetirom.*
This study aims to investigate the differences in intra-urban catchments with different characteristics through real-time wastewater monitoring. Monitoring stations were installed in three neighbourhoods of Barcelona to measure flow, total chemical oxygen demand (COD), pH, conductivity, temperature, and bisulfide (HS) for 1 year. Typical wastewater profiles were obtained for weekdays, weekends, and holidays in the summer and winter seasons.
View Article and Find Full Text PDFThe objective of the present study was to investigate whether fertility differences in bulls are reflected in variations of sperm quality when analysing only one ejaculate per male. Two experiments were performed. In the first experiment, frozen semen samples from 20 adult bulls were tested; 10 bulls had high field fertility and 10 bulls had low field fertility.
View Article and Find Full Text PDFComputer assisted sperm analysis (CASA) systems can reduce errors occurring in manual analysis. However, commercial CASA systems are frequently not applicable at the forefront of challenging research endeavors. The development of open source software may offer important solutions for researchers working in related areas.
View Article and Find Full Text PDFTo date, sperm morphometric studies have assessed whole sperm populations without considering sperm function. The aim of this study was to evaluate the relationship of sperm membrane and acrosomal integrity with sperm morphometry in liquid semen samples collected from bulls. To this end, sperm morphometry was performed on cryopreserved semen samples from 16 bulls by a combination of fluorescent dyes, including Hoechst 33343, carboxyfluorescein diacetate, and propidium iodide.
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