[Treatment of chronic viral hepatitis C with direct acting antiviral agent: review].

HCV infection treatment regimens are viewed from positions of HCV life cycle and replication, effects of NS3/4A protease inhibitors and NS5A/NS5B inhibitors on HCV strain replication. Evolution of HCV treatment regimens from its discovery to modern DAA agents had led to substantial progress although drug resistance poses a new issue to be addressed.

[Effect of Hypecoum erectum extract on morphofunctional state of the liver in rats with tetracycline-associated hepatitis].

The effect of Hypecoum erectum L. extract on the morphofunctional condition of the liver in rats with experimental tetracycline-associated hepatitis was studied. The experiment included 40 albino rats Wistar.

[Effect of plant extracts from Baĭkal region on the choleretic reaction in white rats].

In the given work was estimated the choleretic activity of the extracts that was derived from the plants of the Baikal region. It had been shown that the experimental-therapeutic doses of the extracts stimulate choleretic reaction in intact rats.

[The characteristics of the action of polyphytochol on the course of experimental hepatitis and cholecystitis].

The effect of polyphytochol representing a combination of vegetable agents was studied on models of acute toxic hepatitis caused by CCl4 and cholecystitis. The efficiency of the drug in pathology of the hepatobiliary system was shown: it decreases cholestasis acting as a choleretic and bile-secreting drug, acts on the main pathogenetic links in hepatitis, exerts a marked membrane-stabilizing effect, influences favourably the processes of synthesis in the liver.

[Effect of antihepatotoxic tea on the course of drug-induced hepatitis].

Pharmacotherapeutic efficacy of antihepatoxic tea was studied on an experimental model of tetracycline-induced hepatitis. It was concluded that the tea had a marked pharmacotherapeutic effect on the process of tetracycline-induced hepatitis in animals. It lowered the level of the cytolytic syndrome, prevented the progress of cholestasis and stimulated the bile secretory function of the liver.