Preliminary low-dose photodynamic exposure to skin cancer with chlorin e6 photosensitizer.

Background: The study aimed to investigate the chlorin e6 photosensitizer distribution in the tumor and tumor border (5 mm) during low-dose photodynamic treatment and to increase the effectiveness of the therapy for skin neoplasms.

Methods: Sensitized boundaries of neoplasms were evaluated by video fluorescence imaging. The study of changes in the chlorin e6 distribution before/after photodynamic therapy and in the process of low-dose photodynamic exposure was carried out by the method of spectral fluorescence diagnostics.

[Experimental study of root dentine permeability for medicines].

The use of contemporary endodontic methods of treatment do not always result in elimination of chronic nodus in periodontum, and filled teeth often remain potential noduses of infection, notwithstanding the impression of clinical and roentgenological wellness. Study of permeability of tooth root dentine under effect of medicines and microorganisms was done by means of introduction of colorant into the canal by iodine-electrophoresis method, observation of permeability of medicine from the canal through hard tissues of tooth and inhibition of growth of microorganisms in nutrient medium. It has been found out that the maximum permeability of tooth root dentine was observed in the cervical third of the root.