Early weaning management followed by energy supplementation can lead to metabolic alterations in the calf that exert long-term effects on the animal's health and performance. It is believed that the main molecular basis underlying these metabolic adaptations are epigenetic mechanisms that regulate, activate, or silence genes at different stages of development and/or in response to different environmental stimuli. However, little is known about postnatal metabolic programming in .
View Article and Find Full Text PDFBackground: Migraine is a painful neurological syndrome characterized by attacks of throbbing headache, of moderate to severe intensity, which is associated with photo- and phono- sensitivity as well as nausea and vomiting. It affects about 15% of the world's population being 2-3 times more prevalent in females. The calcitonin gene-related peptide (CGRP) is a key mediator in the pathophysiology of migraine, and a significant advance in the field has been the development of anti-CGRP therapies.
View Article and Find Full Text PDFTetratomidae Billberg, 1820 is a small family of tenebrionoid beetles that primarily feed on polypore fungi. Their Neotropical diversity remains poorly known, with most recent studies concentrating on Nearctic and Palearctic species. The few records from the neotropics are from samplings in the Atlantic Forest or Amazon Rainforest.
View Article and Find Full Text PDFWith population growth and the contamination of ecosystems by pesticides and chemical fertilisers, agriculture faces the challenge of increasing productivity in a sustainable manner. In response to this demand, the global ecological transition has promoted the use of bio-inputs, such as fungi and bacteria, which are essential for agricultural sustainability. However, the extensive use of herbicides in modern agriculture may compromise the effectiveness of these bio-inputs by interfering with their biochemical pathways.
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