Publications by authors named "I P Paster"

Article Synopsis
  • A narrative review was conducted to assess how race and socioeconomic status impact penile cancer rates, revealing higher incidence in underdeveloped regions.
  • HPV-related tumors are more common globally in areas with high rates of HPV and HIV, with socioeconomic factors worsening these disparities.
  • In the U.S., racial disparities were evident, particularly for black men, highlighting the need for targeted education and interventions like HPV vaccination to reduce penile cancer burdens in at-risk populations.
View Article and Find Full Text PDF

Background: Obesity is a well-established risk factor of renal cell carcinoma (RCC), however the impact of obesity on surgical outcomes for racial and ethnic minority patients with RCC is unclear. This study investigated whether a higher body mass index (BMI) or obesity (BMI ≥30 kg/m) was associated with worse perioperative outcomes and if there were heterogeneous effects based on race, ethnicity, and neighborhood-level socioeconomic factor.

Methods: In this single-center cross-sectional study, medical records of patients who underwent partial or radical nephrectomy between 2010 and 2022 were retrospectively reviewed.

View Article and Find Full Text PDF

Treatment of penile cancer (PC) focuses on organ preservation, employing various surgical and non-surgical approaches. These interventions may lead to disfigurement, impacting patients' functional outcomes and psychosocial well-being. We reviewed studies related to penile health and PC up to February 2024, limited to studies published in English.

View Article and Find Full Text PDF

Urothelial carcinoma (UC) is the most common form of bladder cancer (BC) and is the variant with the most immunogenic response. This makes urothelial carcinoma an ideal candidate for immunotherapy with immune checkpoint inhibitors. Key immune checkpoint proteins PD-1 and CTLA-4 are frequently expressed on T-cells in urothelial carcinoma.

View Article and Find Full Text PDF