[Combined effect of hyperglycemia and chemo- and radiation action on the status of metabolic processes in certain experimental sarcomas in rats].

A number of metabolic parametres were studied in subcellular fractions of rat sarcoma 45, M-1 and carcinosarcoma Worker 256. Administration of high doses of glucose amplified some effects of chemotherapeutic drugs and X-ray therapy, which were manifested as follows: a decrease in glycolysis rate, alteration in the rate of redox reactions, shifts in the ratio between glycolysis and biological oxidation in mitochondria. These alterations were determined by the type of sarcoma, by sequence of operations in the procedure and by cytostatic used.

[Aspartate aminotransferase and glutamate dehydrogenase activity in the rat brain during infrared laser exposure].

In experiments in vivo it was shown that upon low-intensity infrared irradiation changes in the activity of main enzymes of glutamic acid metabolism are a function of time of exposure and flux density.

[The content of pyridoxal coenzymes in the brain and liver of rats exposed to a single irradiation with x-rays].

A study was made of the effect of a single exposure of rats to 0.4 Gy X-radiation on the content of pyridoxal phosphate and pyridoxamine phosphate in gray and white brain substances and liver. At the same time changes were noted in the activity of pyridoxal kinase in the tissues under study.

[Brain metabolism of sarcoma 45-bearing rats undergoing radiation and the effect of hyperthermia on the tumor].

Activity of hexokinase and acetylcholinesterase and pyridoxal co-enzyme content of brain subcellular fractions were studied in rats, bearing sarcoma 45, after local exposure of the tumor to 20 Gy X-radiation and microwave hyperthermia. The carbohydrate metabolism was sharply inhibited while the pyridoxal coenzyme content and acetylcholinesterase activity increased.

[Catecholamine content and acetylcholinesterase activity in the brain of rats exposed to lasers].

The catecholamine content was quantitated and acetylcholinesterase activity determined in rat brain locally exposed to laser radiation. It was shown that the adrenaline/noradrenaline ratio changed in the tissues under study and the cholinergic system was involved in the abscopal effect of laser radiation.