[Growth factors and the hystologic picture of the liver in chronic viral hepatitis and hepatic cirrhosis].

The authors of the article present the results of studying correlations between growth factors and histological changes in the liver in 48 patients with chronic viral hepatitis and hepatic cirrhosis. The results show that the blood level of transforming growth factor-beta1 (TGF-beta1) increases, whilst the level of insulin-like growth factor-1 (IGF-1), epidermal growth factors (EGF), and regeneration index (RI) in general decrease according to increase in histological activity and the degree of hepatic fibrosis. There was a positive correlation between TGF-beta1 and a negative one between IGF-1 and EGF, as well as RI, on the one part, and the degree of hepatic inflammation and fibrosis, on the other.

[Clinico-morphological basis of selection of the methods of treatment of echinococcosis of the abdominal organs and retro- peritoneal space].

The work is based on the analysis of surgical treatment of 2,985 patients with hydatid diseases of the organs of the abdominal cavity and retroperitoneal space. The character of the operative intervention is determined by the period of hydatid vital activity, its size, and the features of its localization within the organ. The authors identified the following periods of hydatid vital activity: living parasite, dead parasite; complicated echinococcosis.