Publications by authors named "I P GALPERIN"

Article Synopsis
  • The study aimed to explore how a cognitive-motor rehabilitation program combining treadmill training with virtual reality (TT+VR) impacts frailty in individuals with multiple sclerosis (pwMS).
  • Participants were evaluated in a multicenter trial, with 83 pwMS completing a 6-week intervention to measure changes in frailty using a validated index.
  • Results showed overall improvements in frailty for both training groups, but the TT+VR group had significantly better cognitive-related improvements compared to the treadmill-only group.
View Article and Find Full Text PDF

Background: Trait and state physical fatigue (trait-PF and state-PF) negatively impact many people with multiple sclerosis (pwMS) but are challenging symptoms to measure. In this observational study, we explored the role of specific gait and autonomic nervous system (ANS) measures (i.e.

View Article and Find Full Text PDF

Objective: The purpose of this study was to examine the association between frailty and the quantity and quality of free-living walking and the mediating effect of frailty on the relationship between disability and walking performance in people with multiple sclerosis (MS).

Methods: Ninety-nine people with relapsing-remitting MS (mean age = 49.3 [SD = 9.

View Article and Find Full Text PDF

Background: Motor and cognitive impairments impact the everyday functioning of people with MS (pwMS). The present randomized controlled trial (RCT) evaluated the benefits of a combined motor-cognitive virtual reality training program on key motor and cognitive symptoms and related outcomes in pwMS.

Methods: In a single-blinded, two-arm RCT, 124 pwMS were randomized into a treadmill training with virtual reality (TT + VR) group or a treadmill training alone (TT) (active-control) group.

View Article and Find Full Text PDF

Background: Physical activity is lower in people with multiple sclerosis (pwMS) compared to healthy controls. Previous work focused on studying activity levels or activity volume, but studies of daily-living rest-activity fragmentation patterns, circadian rhythms, and fractal regulation in pwMS are limited. Based on findings in other cohorts, one could suggest that these aspects of daily-living physical activity will provide additional information about the health and well-being of pwMS.

View Article and Find Full Text PDF