Transapical Approach to Septal Myectomy for Hypertrophic Cardiomyopathy.

A 63-year-old symptomatic female with apical hypertrophic cardiomyopathy and diastolic disfunction was admitted to the hospital. What is the best way to manage this patient? This study is a literature review that was performed to answer this question. The following PubMed search strategy was used: 'Hypertrophic obstructive cardiomyopathy' [All Fields] OR 'apical myectomy' [All Fields], NOT 'animal [mh]' NOT 'human [mh]' NOT 'comment [All Fields]' OR 'editorial [All Fields]' OR 'meta-analysis [All Fields]' OR 'practice-guideline [All Fields]' OR 'review [All Fields]' OR 'pediatrics [mh]'.

Redo aortic root surgery post-Ross procedure.

Background: Despite numerous advantages of the Ross procedure, it presents a risk of late autograft and right ventricular outflow tract conduit failure. This study aimed to analyze the outcomes of autograft dysfunction reoperations using autograft-sparing and root replacement techniques.

Methods: Between 2015 and 2023, 49 patients underwent redo root surgery in our institution.

Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial.

Background: Emergence of drug resistance demands novel antimalarial drugs with new mechanisms of action. We aimed to identify effective and well tolerated doses of ganaplacide plus lumefantrine solid dispersion formulation (SDF) in patients with uncomplicated Plasmodium falciparum malaria.

Methods: This open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial was conducted at 13 research clinics and general hospitals in ten African and Asian countries.

A New Criterion for Shear Wave Elastometric Assessment Using Modulus of Stiffness Difference between Object and Environment.

Unlabelled: Ultrasound shear wave elastography is a modern method that is based on measuring the shear wave velocity making it possible to determine stiffness of soft biological tissues at an arbitrary point (point elastography) or to construct a two-dimensional color image with a subsequent point measurement of stiffness (two-dimensional elastography) and therefore to compare the stiffness of an object with a medium or objects with each other. is to develop a new criterion for the comparative assessment of objects with different stiffness during shear wave elastometry: modulus of stiffness difference between object and environment.

Materials And Methods: Using the original technology of building two-dimensional color elastogram, point and two-dimensional shear wave elastography were performed using linear sensors on commercial ultrasound scanners: Aixplorer (SuperSonic Imagine, France), Acuson S2000 (Siemens, Germany), and Verasonics acoustic system (Verasonics Inc.

Early post-septal myectomy outcomes for hypertrophic obstructive cardiomyopathy.

Background: We aimed to evaluate early outcomes of septal myectomy in patients with hypertrophic cardiomyopathy.

Methods: We retrospectively analyzed data collected over a 9-year period from 583 patients who underwent septal myectomy for hypertrophic cardiomyopathy at our institution.

Results: The mean age was 55.