Publications by authors named "I Oshima"
Article Synopsis
- Soft corals have potential pharmaceutical applications, particularly for their antiproliferative and anti-inflammatory properties, with the Alcyoniidae family being a notable source of bioactive terpenoids.
- Despite significant research, their effectiveness against biofouling, specifically against mussels, has not been thoroughly investigated.
- This study successfully isolates a new diterpenoid and 15 known compounds, evaluates their chemical structures, and assesses their anti-biofouling capabilities and toxicities, highlighting the promise of these natural compounds as eco-friendly antifouling agents.
We aimed to determine the effects of maternal nutrient restriction (MNR) on the DNA methylation and gene expression patterns associated with metabolism and immunopoiesis in the thymuses of fetal Wagyu cattle. Pregnant cows were allocated to two groups: a low-nutrition (LN; 60% nutritional requirement; = 5) and a high-nutrition (HN; 120% nutritional requirement, = 6) group, until 8.5 months of gestation.
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- * Chemical analysis and spectroscopic methods were used to determine the structure and absolute stereochemistry of the newly identified compounds.
- * The isolated compounds were tested for anti-biofouling activity against the mussel Mytilus galloprovincialis, with the new compound showing strong potential as a natural anti-biofouling agent.
The marine red algal genus Laurencia has abundant halogenated secondary metabolites, which exhibit novel structural types and possess various unique biological potentials, including antifouling activity. In this study, we report the isolation, structure elucidation, and antifouling activities of two novel brominated diterpenoids, aplysin-20 aldehyde (1), 13-dehydroxyisoaplysin-20 (2), and its congeners. We screened marine red alga Laurencia venusta Yamada for their antifouling activity against the mussel Mytilus galloprovincialis.
View Article and Find Full Text PDFThis study aimed to elucidate the effects of maternal undernutrition (MUN) on epigenetic modification of hepatic genes in Japanese Black fetal calves during gestation. Using a previously established experimental design feeding the dams with 60% (LN) or 120% (HN) of their global nutritional requirements during the 8.5-month gestational period, DNA methylation in the fetal liver was analyzed with reduced representation bisulfite sequencing (RRBS).
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