Publications by authors named "I Okoye"
Background: Understanding knowledge of human immunodeficiency virus (HIV) status and timely linkage to care are crucial for improving health outcomes among individuals living with HIV. This study analyzes trends in HIV knowledge status and linkage to care using data from America's HIV Epidemic Analysis Dashboard (AHEAD) National Database.
Methods: A retrospective database analysis was conducted utilizing the AHEAD National Database, focusing on individuals diagnosed with HIV from 2017 to 2022.
The primary goal of program communication in public health is to influence behaviors. It also aims to raise awareness and ultimately improve health outcomes. Under the umbrella of program communication exist three interconnected, interrelated, and mutually supportive communication aspects: advocacy, communication, and social mobilization (ACSM).
View Article and Find Full Text PDFTadalafil pretreatment attenuates doxorubicin-induced hepatorenal toxicity by modulating oxidative stress and inflammation in Wistar rats.
Toxicol Rep
December 2024
Doxorubicin (DOX) is a widely used anticancer agent, but its clinical application is limited by significant off-target hepatorenal toxicity. Tadalafil (TAD), a selective phosphodiesterase-5 inhibitor used mainly for erectile dysfunction and pulmonary arterial hypertension, has shown potential in reducing oxidative stress. This study investigated TAD's chemoprotective effects and underlying mechanisms in DOX-induced hepatorenal toxicity in rats over 12 days.
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- Nigeria received nearly 4 million COVID-19 vaccine doses through the COVAX Facility to address vaccine distribution, yet there is limited research on optimizing vaccination efforts from the perspective of mobile teams.
- The study focused on the experiences of 12 mobile vaccination teams in Benue and Niger states, utilizing focus group discussions to identify themes related to their perceptions of vaccination challenges and successes.
- Results showed that health workers felt their efforts led to increased vaccine coverage and accessibility, though they faced challenges such as misconceptions about the vaccine, demands for incentives, and logistical issues like poor connectivity and stock shortages.
The secretion of alarmin cytokines by epithelial cells, including thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, initiates inflammatory cascades in asthma. However, alarmin cytokine expression in the upper airways in asthma remains largely unknown. We recruited 40 participants with asthma into four groups as per the Global Initiative for Asthma (GINA) steps (10 in each group of GINA 1/2, 3, 4, and 5).
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