Publications by authors named "I Obando"
is a major pathogen in children, elderly subjects, and immunodeficient patients. Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule (PRM) involved in resistance to selected microbial agents and in regulation of inflammation. The present study was designed to assess the role of PTX3 in invasive pneumococcal infection.
View Article and Find Full Text PDFMolecular epidemiology of pneumococcal carriage in children from Seville, following implementation of the PCV13 immunization program in Andalusia, Spain.
Enferm Infecc Microbiol Clin (Engl Ed)
April 2024
Introduction: The 13-valent pneumococcal conjugate vaccine (PCV13) universal vaccination programme was introduced in December 2016 in Andalusia.
Methods: A cross-sectional study was conducted on the molecular epidemiology of pneumococcal nasopharyngeal colonization. A total of 397 healthy children were recruited from primary healthcare centres in Seville for the periods 1/4/2018 to 28/2/2020 and 1/11/2021 to 28/2/2022 (PCV13 period).
SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been affected, and although infection generally presents as a mild disease, some have developed the Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS).
View Article and Find Full Text PDFArticle Synopsis
- This study evaluated how the introduction of the pneumococcal conjugate vaccine 13 (PCV13) affected the occurrence and types of invasive pneumococcal disease (IPD) in children in Andalusia between 2018 and 2020.
- The incidence of IPD initially rose slightly from 2018 to 2019 but then significantly decreased in 2020, with the cases attributed to PCV13 serotypes dropping from 28% compared to earlier years (2006-2009).
- Non-PCV13 serotypes such as 24F and 11A emerged as common strains during the study period, raising concerns about their potential for invasiveness and antibiotic resistance, indicating a need for ongoing
Introduction: The educational level of the adult population is related to obesity, but there is little knowledge regar ding the relationship of parents' educational level with the obesity and muscle strength of Chilean pre-school children.
Objective: To describe the levels of adiposity and muscular strength of pre schoolers, according to the educational level and socio-demographic characteristics of their parents.
Patients And Method: Descriptive, cross-sectional study with participation of pre-schoolers from kindergartens and their parents (n = 99).