Publications by authors named "I O Ribeiro"
Background: Alzheimer's disease (AD) is a neurodegenerative disorder that has become increasingly prevalent around the world and can be characterized in vivo by amyloid-beta peptide and hyperphosphorylated tau protein. Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are potential previous stages of AD dementia. Behavioral and psychological symptoms are common in SCD and MCI, but their biological basis is still not clarified.
View Article and Find Full Text PDFMild cognitive impairment (MCI) refers to cognitive alterations with preservation of functionality. Individuals with this diagnosis have a higher risk of developing dementia. Non-pharmacological interventions, such as physical exercise, are beneficial for the cognition of this population.
View Article and Find Full Text PDFBackground: Active commuting benefits both individual and planetary health. Estimating commuting behavior is desirable, although very challenging in large and regionally relevant nations like Brazil.
Methods: This review (CRD42023431054) included observational studies that estimated prevalence of active commuting in Brazil for adults (≥18 y).
Article Synopsis
- The Developmental Origins of Health and Disease (DOHaD) concept links early adverse conditions, like maternal protein restriction, to chronic diseases, specifically prostate cancer (PCa).
- The study investigated the expression of piwi-interacting RNAs (piRNAs) in the ventral prostate of rat offspring affected by maternal malnutrition, revealing developmental delays and altered tissue structures.
- Findings suggest that maternal malnutrition influences piRNA expression, which may have long-term effects on prostate health and increase the risk of disorders as the offspring age.