Publications by authors named "I O Igbokwe"
Effect of Zinc Supplementation on Altered Calcium Homeostasis, Parathyroid Gland, Bone, and Skeletal Muscle Histology Induced by Subchronic Oral Exposure to Glyphosate-Based Herbicide (GOBARA) in Wistar Rats.
Clin Pathol
July 2024
Article Synopsis
- The study aimed to evaluate how zinc supplementation affects calcium balance and tissue health in rats exposed to glyphosate-based herbicide toxicity.
- Results showed that glyphosate exposure led to lower calcium and vitamin D levels, increased parathormone, and tissue damage in the parathyroid gland, bone, and muscle cells.
- Zinc pretreatment appeared to reduce these harmful effects, indicating a protective role against glyphosate-induced health issues.
Objectives: To evaluate the effect of zinc supplementation on immunotoxicity induced by subchronic oral exposure to glyphosate-based herbicide (GBH).
Methods: Sixty adult male Wistar rats randomly divided equally into six groups were exposed to GBH by gavage daily for 16 weeks with or without zinc pretreatment. Group DW rats received distilled water (2 mL/kg), group Z rats received zinc (50 mg/kg), and group G1 and G2 rats received 187.
African swine fever (ASF) is a highly contagious fatal infectious disease of pigs and wild suids. The disease has a worldwide occurrence and significant impact on pig production. Two adult intensively raised large white boars from two farms in Jos with a history of sudden death were diagnosed of ASF between July and August 2019.
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- The study evaluated how zinc pretreatment affects liver and kidney damage in rats exposed to glyphosate-based herbicides over an extended period.
- After exposure to the herbicide, various serum markers indicated liver and kidney toxicity, with significant damage observed in organ tissues.
- Zinc pretreatment helped reduce some of the toxic effects in the blood, but it did not completely prevent the tissue damage associated with glyphosate exposure.
Adoption and failure rates of vaccinations for disease prevention in chicken farms in Jos, Nigeria.
Trop Anim Health Prod
November 2020
Vaccinations against diseases to prevent disease outbreaks are strategic to disease prevention, but vaccination failures may constitute a challenge in practice. This study was aimed at assessing the adoption and failure rates of vaccinations in 80 chicken farms in Jos, Nigeria. Data were obtained through a structured questionnaire validated by interviews and checking of farm and veterinary records.
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