Publications by authors named "I O Assis"
Albumin-based nanoparticles (ABNPs) represent promising drug carriers in nanomedicine due to their versatility and biocompatibility, but optimizing their effectiveness in drug delivery requires understanding their interactions with and uptake by cells. Notably, albumin interacts with the cellular glycocalyx, a phenomenon particularly studied in endothelial cells. This observation suggests that the glycocalyx could modulate ABNP uptake and therapeutic efficacy, although this possibility remains unrecognized.
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- Obesity is a complex disease linked to various health issues, influenced by how our body stores fat, and some people with obesity don't develop metabolic syndrome.
- The study recruited 305 individuals with severe obesity and 196 normal-weight controls, collecting various health metrics while analyzing genetic variants associated with fat storage.
- Results showed that certain gene polymorphisms, particularly rs7895833, rs1467568, and rs660339, were linked to the likelihood of developing severe obesity and associated physical traits, indicating potential genetic markers for obesity risk.
To achieve the objective of this study, we conducted a narrative review on physical therapeutic modalities applied to prevent functional losses associated with human T-lymphotropic virus 1 (HTLV-1) infections to promote health education and viable and accessible alternatives in the development of health education technology adapted to the home environment. This study comprised a qualitative stage of theoretical development to construct a digital booklet with an observational basis based on studies that reiterate themes about educational technologies as tools to conduct a home protocol of guided exercises without the direct supervision of professional physical therapists. Results indicate a lack of research on the development of health education technologies to assist patients with HTLV-1 without tropical spastic paraparesis or HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
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- - Bats are known to carry various viruses, including different types of adenoviruses, with ten species of bat adenoviruses (BtAdV A to J) identified globally.
- - In Brazil, a study collected swabs from 208 bats across three states to detect and analyze the genetic diversity of BtAdVs in the Atlantic Forest, finding a 7.7% detection rate among multiple bat species.
- - The phylogenetic analysis revealed high genetic diversity and identified eleven new potential species of BtAdV (BtAdV K to U), contributing valuable information to the understanding and monitoring of adenoviruses in this region.
Herein we report the synthesis of transition-metal-free potassium borophosphate glasses and their application as bactericidal and bacteriostatic material. The antimicrobial activity was achieved through a simple change in the molar ratio of boron and phosphorus atoms, making borophosphate glass soluble in water. The glasses were analyzed by X-ray powder diffraction, Raman spectroscopy, laser-induced breakdown spectroscopy, and water absorption.
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