Publications by authors named "I Novakovic"
A Machine Learning Approach to Gene Expression in Hypertrophic Cardiomyopathy.
Pharmaceuticals (Basel)
October 2024
Article Synopsis
- Hypertrophic cardiomyopathy (HCM) is a heart condition marked by thickening of the heart muscle, heightening the risk for serious heart issues, and this study looks into the expression of certain genes related to cell death (apoptosis) as potential markers for the disease's progression.
- Blood samples from 93 HCM patients were analyzed using quantitative real-time PCR (qPCR) to assess gene expression and study the relationship between these genes and clinical parameters.
- Results showed that many HCM patients had lower levels of specific apoptosis-regulating genes, whereas BAX and another gene were elevated in a significant number of cases, indicating a possible protective response in the heart, which may be explored further for improving treatment outcomes
Article Synopsis
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Basil ( L.) is a widely used culinary herb. In this study, ethanol, dichloromethane, and sunflower oil were used separately as solvents with distinct polarities for the extraction of basil aerial parts to simulate the different polarity conditions in domestic food processing.
View Article and Find Full Text PDFBackground: Among many genes which have been analyzed to understand obesity and related metabolic traits among children and adolescents, not many studies are conducted on LGALS3 gene, especially in population of children. A positive correlation of circulating galectin 3 serum levels with impaired blood glucose, high blood pressure and higher values of serum lipids and was found in general population. The aim was to investigate possible association of rs4644 with body mass index, glycaemia, and lipid profile in Serbian adolescents.
View Article and Find Full Text PDFIn this paper, three different Zn(II) complexes with ()-2-(2-(1-(6-bromopyridin-2-yl)ethylidene)hydrazinyl)-,,-trimethyl-2-oxoethan-1-aminium chloride (HLCl) have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis, IR and NMR spectroscopy. All complexes are mononuclear, with the ligand (L) coordinated in a deprotonated formally neutral zwitterionic form NNO donor set atoms. Complex 1 forms an octahedral geometry with the composition [ZnL](BF), while complexes 2 [ZnL(NCO)] and 3 [ZnL(N)] form penta-coordinated geometry.
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