Development of three ways molecular logic gate based on water soluble phenazine fluorescent 'selective ion' sensor.

New hydrophilic fluorescent selective ion sensor based on phenazine and phthalazine moieties, 1,1'-(phenazine-2,3-diyl)-bis(3-(1,4-dihydroxyphthalazin-6-yl)urea) (1), has been designed, synthesized and characterized. Interestingly, sensor 1 exhibits prominent "turn-on" and "turn-off" fluorogenic signaling at 580 nm towards Fe & AcO and Sr & Cu, respectively. The fluorescence titration experiments shed light on the nature of the interaction between 1 and guest molecules (Fe, Sr, Cu and AcO), which divulge that 1 is flexible enough to orient itself according to the size of the guest molecule.

Fluorenone based fluorescent probe for selective "turn-on" detection of pyrophosphate and alanine.

To sense biologically important entities with different size and dimensions, a fluorenone based fluorescent receptor was designed and synthesized. Probe 1 displayed a distinct fluorescence enhancement emission at 565nm for pyrophosphate and 530nm for alanine in polar solvent. The fluorescence titration experiments confirm 1:1 stoichiometric ratio with high-binding constant and very low limit of detection (LoD) values.