On the palliative care ward, we treated a man with a small cell lung cancer who was suffering from vertigo for six years, however the vertigo got stronger the last six months with pronounced coordination disorders. After several examinations, the cause was a paraneoplastic neurologic syndrome (PNS) with Hu-antibodies. PNS are various neurological malfunctions, which occur mostly in certain patterns.
View Article and Find Full Text PDFSenescence impairs liver physiology, mitochondrial function and circadian regulation, resulting in systemic metabolic dysregulation. Given the limited research on the effects of combined exercise on an ageing liver, this study aimed to evaluate its impact on liver metabolism, circadian rhythms and mitochondrial function in senescence-accelerated mouse-prone 8 (SAMP8) and senescence-accelerated mouse-resistant 1 (SAMR1) mice. Histological, reverse transcription quantitative polymerase chain reaction (RT-qPCR) and immunoblotting analyses were conducted, supplemented by transcriptomic data sets and AML12 hepatocyte studies.
View Article and Find Full Text PDFEur J Transl Myol
August 2024
There has been an increasing interest among CrossFit® coaches and practitioners in identifying indicators of sport performance. This study aimed to examine the correlation between anthropometric measures, cardiorespiratory capacity, power, local muscle endurance, and total athleticism score, with performance in the CrossFit® Open 2021. Fourteen male volunteers (aged 30.
View Article and Find Full Text PDFJ Nutr Biochem
December 2024
Although previous studies demonstrated that the ancestral lifestyle can enhance the metabolic health of offspring exposed to an obesogenic diet, the specific connections between these positive effects in redox state and telomere length are unknown. We investigated the impact of paternal resistance training (RT) on stress-responsive signaling and the pathways involved in telomere homeostasis in skeletal muscle. This investigation encompassed both the fathers and first-generation litter exposed to a long-term standard diet (24 weeks) and high fat diet (HFD).
View Article and Find Full Text PDFEutrophication has become a recurrent concern in reservoirs worldwide. This problem is intensified in tropical semiarid regions, where the reservoirs have high seasonal and annual variability of water level and volume. Therefore, an extensive understanding of the diel variation of water quality key-parameters can help improve management of such reservoirs.
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