Diagnostic value of 99mTc-HM-PAO leukocyte scintigraphy and computer tomography in patients with sternal wound infections.

Methods: 99mTc-HM-PAO leukocyte scintigraphy (LS) and computer tomography (CT) were carried out on 19 patients after cardiac surgery; 10 patients with a high clinical probability of an infected sternal wound (group II) and additionally 9 postoperative patients without clinical symptoms of infection, as a control group (group I). LS was carried out with mixed, autologous leukocytes, labelled with 99mTc-HM-PAO in vitro. CT scans were obtained with the use of intravenous contrast material.

[Experiences with the use of ioxithalamate (Telebrix)].

The effects of Ioxitalamate/Telebrix-BYK GULDEN were tested for excretion urography and various angiographic applications and in animal experiments (selective renal angiography in 36 dogs). The contrast medium was well tolerated and the radiographs were of good quality. Significant effects were not detected, neither in blood pressure, heart rate and ECG, nor in Se-creatinine, nor in UN-, SGOT and Se-bilirubin values.

[Significance of low osmolarity contrast media in state of the art roentgen diagnosis].

The authors used low-osmolality contrast material intravascularly in 546 patients, in 371 cases ioxaglate, in 80 patients iopamidol and in 95 iohexol. On each occasion good detail-rich pictures were obtained. Sensation of heat was indicated only by 1 patient (iopamidol), pain by 7 patients (ioxaglate 4, iohexol 2, iopamidol 1).

Investigations on the acute toxic, cytogenetic, and embryotoxic activity of phenyl isocyanate and diethoxyphosphoryl isocyanate.

Phenyl isocyanate (I) and diethoxyphosphoryl isocyanate (II), used as intermediates in organic chemical syntheses, were tested for their acute toxic, cytogenetic, and embryotoxic activity on mice of different strains. The oral LD50 values for male CFLP mice were determined to be 196 mg/kg for I and 4080 mg/kg for II. Single oral doses of 1/40 and 1/20, respectively, of the LD50 of I (4.