Publications by authors named "I Negoescu"

Article Synopsis
  • - A 66-year-old man with a long history of smoking was diagnosed with rheumatoid arthritis in 2018 and later developed interstitial pulmonary fibrosis in 2020, treated with nintedanib in 2022.
  • - Despite showing some clinical improvement, his condition remained serious and progressive, ultimately leading to death from pulmonary thromboembolism.
  • - An autopsy revealed severe complications related to rheumatoid arthritis including lung interstitial lesions, bronchiectasis, and vascular damage caused by chronic inflammation.
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Hydatid disease remains endemic in many parts of the world, most notably the Mediterranean region, Australia, New Zealand, the Middle East, and South America. Plurivisceral echinococcosis is defined as the concomitant or successive presence of hydatidosis in more than one internal organ. It has been noticed that the number of cases with multi-organ localizations and multiple cysts has increased in the last years.

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The authors studied the ultrastructure of benign and malignant forms of the thyroid cold nodule. In the benign cold nodule the most striking feature was an irregular endoplasmic reticulum with large cisternae and scarce ribosomes, this meaning an impaired protein synthesis. Frequent lysosomes and phagolysosomes occurring in the apical zone of the cell were present.

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After 30 years of iodine prophylaxis the incidence of goiter in the Valea Jiului area was reassessed. A number of 7,892 pupils aged 7-16 years were examined, of whom goiter was found in 32%. Before iodine prophylaxis started the incidence was 91.

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