Publications by authors named "I Nava"
With the growth of the quantum biology field, the study of magnetic field (MF) effects on biological processes and their potential therapeutic applications has attracted much attention. However, most biologists lack the experience needed to construct an MF exposure apparatus on their own, no consensus standard exists for exposure methods, and protocols for model organisms are sorely lacking. We aim to provide those interested in entering the field with the ability to investigate static MF effects in their own research.
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- Anemia and hyperferritinemia are common at the onset of Gaucher disease, affecting 41% and 51% of patients respectively.
- Over a 5-year period, enzyme replacement therapy (ERT) significantly improved hemoglobin levels, decreased markers of ineffective erythropoiesis, and reduced serum ferritin, indicating better iron metabolism.
- The study highlights the important role of iron dysregulation in anemia for Gaucher disease patients and shows that ERT enhances both erythropoiesis and iron handling.
Alternative cleavage and polyadenylation (APA) often results in production of mRNA isoforms with either longer or shorter 3' UTRs from the same genetic locus, potentially impacting mRNA translation, localization, and stability. Developmentally regulated APA can thus make major contributions to cell type-specific gene expression programs as cells differentiate. During spermatogenesis, ∼500 genes undergo APA when proliferating spermatogonia differentiate into spermatocytes, producing transcripts with shortened 3' UTRs, leading to profound stage-specific changes in the proteins expressed.
View Article and Find Full Text PDFAlternative Cleavage and Polyadenylation (APA) often results in production of mRNA isoforms with either longer or shorter 3'UTRs from the same genetic locus, potentially impacting mRNA translation, localization and stability. Developmentally regulated APA can thus make major contributions to cell-type-specific gene expression programs as cells differentiate. During spermatogenesis, approximately 500 genes undergo APA when proliferating spermatogonia differentiate into spermatocytes, producing transcripts with shortened 3' UTRs, leading to profound stage-specific changes in the proteins expressed.
View Article and Find Full Text PDFWe present the complete chloroplast genome sequence of an endophytic sp. isolated from a 19th-century coralline red algal specimen from St. Croix, U.
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