"AMPHICEZINE": NEW APPROACHES TO FIGHTING CANCER PRELIMINARY THEORETICAL AND EXPERIMENTAL (IN VITRO) MESSAGE.

Objectives - strategic objective - creation of fundamentally new inhibitors of metastasing of malignant tumors due to the radical surgeries carried out on them. Specific tactical objective - revealing the possible cytolytic and citostatic effectiveness of the drug "Amphicezine" created by us on atypical fibroblastic cells. The effect of "Amphicezine" on viable D60 p4 line cell count was measured using live cell imaging as a measure of cell proliferation.

[Heparin prophylaxis of thrombohemorrhagic complications in surgical interventions in cancer patients].

Patients with uterine (394), ovarian (272) and breast cancer (122) were followed postoperatively using complex clinico-biomicroscopic method. Control (no heparin) group 1 included 100 patients and control group 2 (prophylactic mini-doses of heparin pre- and postoperatively)--142. Intra- and postoperative heparin was administered for prevention of thrombohemorrhagic syndrome (THS) in a study group of 152 patients.