Mask wearing affects emotion perception.

To reduce the spread of COVID-19, mask wearing has become ubiquitous in much of the world. We studied the extent to which masks impair emotion recognition and dampen the perceived intensity of facial expressions by naturalistically inducing positive, neutral, and negative emotions in individuals while they were masked and unmasked. Two groups of online participants rated the emotional intensity of each presented image.

Parametric studies of selective D1 or D2 antagonists: effects on appetitive and feeding behaviour.

Dopamine receptor antagonists have long been known to suppress food intake. The main purpose of the present series of experiments was to investigate feeding in rats across several paradigms evaluating the effects of selective dopamine D1 and D2 antagonists. The selective D1 antagonist, SCH 23390, reduced FR8 operant responding for food (0.

Symptomatic relief from treatment-induced psychosis in Parkinson's disease: an open-label pilot study with remoxipride.

Current treatment strategies for levodopa-induced psychosis in Parkinson's disease have had limited success. Remoxipride, a selective D2 receptor antagonist, was administered in an open label pilot study to seven parkinsonian patients exhibiting thought disorder. Symptoms improved significantly in six patients after treatment durations of 1-6 months and cleared completely in two individuals.

Neurotransmitter replacement therapy in Alzheimer's disease.

The relative success of symptomatic attenuation of motor dysfunction in Parkinson's disease with dopaminomimetics has spurred interest in neurotransmitter replacement therapy for treating Alzheimer's disease. While cholinergic dysfunction has been linked to various clinical parameters in Alzheimer's disease, cholinergic replacement, including precursor therapy, administration of direct-acting agonists and inhibition of enzymatic degradation has had only very modest success. The inhibition of enzymatic degradation has perhaps shown the most interesting results to date.

Selection of children with cerebral palsy for conductive education and the characteristics of children judged suitable and unsuitable.

The method of selection of children for conductive education and their characteristics were studied at the Birmingham Institute. A comparison group allowed evaluation of those judged unsuitable for conductive education. It was found that only approximately 35 per cent of children with cerebral palsy are suitable for conductive education, although those accepted have a wide range of abilities; a wide range of conditions make children unsuitable for conductive education; and the majority of parents with potentially suitable children do not seek conductive education.