Publications by authors named "I N Mikhailov"

Article Synopsis
  • - The study focuses on cancer-associated fibroblasts (CAF) in tumors, particularly looking at the markers FAP and PDGFR in bladder and prostate cancers, noting the complexity and variation of CAF functions in tumor development.
  • - Researchers analyzed tissue samples from 34 prostate cancer patients and 44 bladder cancer patients to identify the relationship between CAF markers and cancer characteristics like stage, morphology, and survival.
  • - Findings show that FAP is linked to metastasis and recurrence in prostate cancer, while its presence is exclusive to invasive bladder cancers, highlighting FAP's potential as a significant marker for diagnosing and understanding treatment resistance in genitourinary tumors.
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Using the self-consistent field approach, we studied the salt-controlled vertical segregation of mixed polymer brushes immersed into a selective solvent. We considered brushes containing two types of chains: polyelectrolyte (charged) chains and neutral chains. The hydrophobicity of both types of chains is characterized by the Flory-Huggins parameters χC and χN, respectively.

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Common femoral artery (CFA) bifurcation is a critical arterial segment of the lower extremities. Dos Santos J.C.

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Spinocerebellar ataxia type 1 (SCA1) is a debilitating neurodegenerative disorder of the cerebellum and brainstem. Memantine has been proposed as a potential treatment for SCA1. It blocks N-methyl-D-aspartate (NMDA) receptors on neurons, reduces excitotoxicity and decreases neurodegeneration in Alzheimer models.

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Background And Objective: Image segmentation is an essential component in medical image analysis. The case of 3D images such as MRI is particularly challenging and time consuming. Interactive or semi-automatic methods are thus highly desirable.

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